Cayos Zapatilla Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Cayos Zapatilla Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino
Megapolis Hotel Panamá
Casa Mallet by Wynwood House
Central Hotel Panama Casco Viejo
Hotel Riu Plaza Panama

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Cayos Zapatilla Hotel Deals

Hotel Eclypse de Mar Acqua Lodge

Hotel Eclypse de Mar Acqua Lodge

3 out of 5
Bocas del Toro Bastimentos
The price is CA $117 per night from Nov 13 to Nov 14
CA $117
CA $129 total
Nov 13 - Nov 14
includes taxes & fees
9.2/10 Wonderful! (117 reviews)
"Our over the water bungalow was so clean, scenic and comfortable. The staff are amazing. Everyone was smiling, accommodating and wonderful. The food in the restaurant was delicious. Very serene and calming, and just it couldn't ask for anything more. The grounds are impeccable and beautiful in a ..."

Reviewed on Nov 7, 2026

Hotel Eclypse de Mar Acqua Lodge
Cosmic Crab Resort

Cosmic Crab Resort

3 out of 5
Carenero Island Trail Bocas del Toro Bocas del Toro
The price is CA $72 per night from Nov 19 to Nov 20
CA $72
CA $79 total
Nov 19 - Nov 20
includes taxes & fees
8/10 Very good! (151 reviews)
"I have been traveling to Cosmic Crab for 9 years. It is one of my favorite places. The resort has a rustic Caribbean vibe with one of the best sunset views in Bocas. The pool is lovely. The restaurant has delicious food. I recommend the fresh fish dishes, burgers, and pizza. The bloody Mary's and ..."

Reviewed on Oct 31, 2026

Cosmic Crab Resort
Hotel Bocas del Toro

Hotel Bocas del Toro

3.5 out of 5
Calle Nº 2 Bocas del Toro Bocas del Toro
Fully refundableReserve now, pay when you stay
The price is CA $131 per night from Dec 13 to Dec 14
CA $131
CA $144 total
Dec 13 - Dec 14
includes taxes & fees
9/10 Wonderful! (205 reviews)
"Great room overlooking the water with a nice comfortable covered balcony. Right in the middle of many bars restaurants and shopping. All of the staff were super friendly!"

Reviewed on Oct 11, 2026

Hotel Bocas del Toro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Cayos Zapatilla vacation package cost?
We make it easy to see the world, with Cayos Zapatilla packages starting from as low as CA $1,332. You'll have the flexibility to bundle your preferred airlines, hotels and car rental. For the ultimate getaway, why not add some tours and activities to your itinerary?
How do I get a cheap travel package to Cayos Zapatilla?
Combining your flight and hotel with Expedia won't just save you time — it'll save you money too. A Cayos Zapatilla vacation package makes it simple to put together your ideal trip. With more than 550 airlines worldwide to select from, finding convenient flights that fit your busy schedule won't be a challenge. In addition to that, we've got over 1,000,000 properties globally to choose from. Now that's choice! No matter who you are, Expedia puts more of the world within your reach.
How far in advance should I book my Cayos Zapatilla vacation?
It can be tricky to know when is the perfect time to book your trip to Cayos Zapatilla. But usually the earlier you book, the cheaper the prices. In some cases, you can secure your flights and hotels nearly a year before departure. If you're thinking of a last-minute getaway, no need to worry! There are plenty of fantastic deals featured on Expedia every single day.
What does an Expedia Cayos Zapatilla travel package include?
That's up to you. You can choose from a range of Cayos Zapatilla packages, such as a rental car, flight and hotel. You can also book a hotel and a flight, or a flight with a rental car. Once you've made your booking, you can add the fun stuff like activities and experiences. Whatever your ideal Cayos Zapatilla getaway looks like, you're sure to save!
What should I know before booking a Cayos Zapatilla travel package?
You'll pick up amazing savings when you bundle your flights, hotels and rental cars into a travel package. Plus, booking everything in one place just makes things easier. So why waste money or time? Whether you're putting together a luxury city stay with your love or a budget family adventure, browse our package deals today.
Can I choose my airline with a Cayos Zapatilla Expedia vacation package?
Definitely. Expedia has more than 550 airline partners to select from across the world. With so much choice, finding the ideal carrier to get you to Cayos Zapatilla will be a snap.
If I'm not able to travel, can I cancel my Cayos Zapatilla vacation package?
Yes, you can. We realize even the best-laid plans can go awry, so we're here to help if you have to make changes to your Cayos Zapatilla vacation package. It may be possible to change or cancel your itinerary for free if you've booked in the last 24 hours. Your airline, hotel or car rental company may impose a fee if your booking was made more than 24 hours ago. Head to our Customer Service Portal for further information. Also, check your itinerary for the finer details on change fees.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.